How Does Eating Healthy Affect Your Life? Essay

You already know healthy eating can have a positive impact on your life, but just how far do these benefits extend? Evidence suggests regularly eating healthy, well-balanced meals contributes to sustained weight maintenance, a better mood, increased energy levels, positive inspiration to others and the potential for a heightened quality of life. Weight Maintenance Following a healthy eating plan — one which emphasizes many fruits and vegetables, whole grains, low-fat dairy products and lean proteins, as well as low levels of saturated and trans fats and low cholesterol, sodium and sugar — contributes to weight maintenance. Staying within your recommended daily calorie intake and eating moderately sized meals also helps you maintain a healthy weight throughout your life. A healthy weight is linked to a reduced risk of many debilitating, chronic diseases, such as diabetes and heart disease, as well as improved self-esteem and mental state. Maintaining a healthy weight is also linked to a lower incidence of depression, meaning healthy eating can help significantly improve the quality of your life. Mood Healthy eating can have a positive impact on your life by leading to a more sustained elevated mood. According to Susan Biali, M.D., in â€Å"Psychology Today,† a healthy lifestyle — including a regular, healthy breakfast, balancing your lean protein consumption with whole-grain carbohydrates, getting enough folate and omega-3 fatty acids and cutting back on alcohol and simple sugars — has been linked to an improved mood and may even help alleviate depression. Carbohydrates allow the amino acid tryptophan to enter the brain where it produces serotonin — the mood-enhancing neurotransmitter, but whole-grain carbohydrates produce a more lasting effect on mood, while carbohydrates made with refined grains, like white bread, cause a quick crash. Energy Eating the right nutritive foods can also boost your energy levels, making you prepared to face each day. Sports nutritionist Rebecca Scritchfield  noted in â€Å"Washington Running Report† in 2009 that adequate levels of the mineral iron, which carries oxygen throughout the body, contribute to sufficient energy levels. Healthy, leafy greens, like spinach, are rich sources of iron. â€Å"Arthritis Today† recommends steering clear of fattening, fried foods — which give you a quick burst of energy but leave you feeling depleted soon thereafter — and stocking up on healthy snacks like nuts, fruit, yogurt and low-fat cheese for an energy boost. Drinking enough water and only consuming moderate amounts of caffeine and sugar also help regulate your energy levels. Inspiring Others Eating healthy doesn’t just directly impact your own life, it can help inspire those around you as well. Healthy eating, and even weight loss, is contagious, according to the â€Å"International Journal of Behavioral Nutrition and Physical Activity,† and you can help the people you care about take care of themselves and achieve greater longevity. While eating better and maintaining your own weight, you can feel confident you have not only worked to improve your life, but also improved the lives of your loved ones. When the people around you — be they friends or family — are happy and positive, this contributes to a better quality of life for all. Healthy Eating Why should I make healthy food choices? Eating a healthy, balanced diet provides nutrients to your body. These nutrients give you energy and keep your heart beating, your brain active, and your muscles working. Nutrients also help build and strengthen bones, muscles, and tendons and also regulate body processes, such as blood pressure. Good nutrition can lower your risk of developing a range of chronic diseases. For example, eating more fruit and vegetables can help lower blood pressure and may lower your risk of certain types of cancer (such as colorectal, breast, lung and prostate cancer). Eating less saturated fat may also lower your risk of heart disease. Healthy eating can also help people that already have some types of disease or illness such as diabetes, high cholesterol and blood pressure. And, of course, improving your eating habits will contribute to you achieving and maintaining a  healthy weight. Try to achieve a balance with the foods you eat and include lots of variety and remember, all things in moderatio n.

Manuela Almeida

The teenage years are for some the most traumatic or wonderful years they will ever experience.   Many experiences through these years decide how individuals will act as adults, the paths they will take in life, the careers they will choose, and if and how they raise their families.   I remember a choice that I made as a teenager that would forever change my life.   To this day, that choice still affects me. Choosing not to go to a party with my friends saved my life.   My friends were in a terrible car accident leaving the party, and one of them did not survive.   This experience has affected the choices I make today.   Because of the loss of my friend, I do not take unnecessary risks, I monitor my behavior in social situations, and I have a greater respect for life. Losing my friend when I was a teenager has made me very cautious about getting into potentially dangerous situations.   Just as the night I chose not to go to the party, I often opt out of celebrations that involve alcohol or have the potential to offer drugs.   I usually will go to the coffee shop or to dinner with a friend or family member instead.   Potentially dangerous or volatile friends scare me as well.   I don’t get close to risk takers for the fear of losing them. My group of friends in high school was a little bit wild, and since the night of the party that took my friend’s life, I have changed my circle of friends.   I don’t go to the clubs to drink, but will go to dance every now and again if I am going with another friend who is also planning on staying sober.   Even when I stay in, I do not partake in risky behaviors.   I do not drink alcohol or take drugs.   Unnecessary risks are just that; unnecessary. â€Å"Going out† doesn’t mean the same thing to me now as it did to me in high school.   Then, it was all about finding a place to party, listening to music, drinking alcohol illegally, and â€Å"hooking† up with people.   Since that fateful night years ago, I monitor my behavior in social situations very carefully.   Before even going out, I make sure that I have a safe friend to accompany me. I make sure that I am always prepared with a cell phone and extra money in case something happens and that someone in my family knows where I am at all times.   When I do go to a club to do some dancing, I don’t drink, and I leave well before 1 a.m., which is when people seem to be getting the most drunk and impaired.   Again, I try not to attract any risky people by portraying myself as wild.   I keep a careful eye on what is going on around me at all times.   I can still have fun, don’t get me wrong, but my friend’s death is never far from my memory when I am around alcohol. Since the loss of my friend, I value life much more.   As a teen, I thought I was invincible and that I knew it all, as most teens do.   I snuck around behind my parent’s backs without permission to do the things I wanted to do.   I knew it was wrong, but I didn’t care.   I did not see the value in my young life and the potential that I had for my future.   I did not care about my parents or family members’ feelings; I was very self-centered.   I just wanted to have fun and â€Å"live my life†. The moment I lost my friend, I realized that the only people who were guaranteed to be there for me through my life were my parents and my family.   I turned to them for support and guidance through the ordeal.   They became more special to me than they had been in a long time, and I valued them.   I also valued myself more since I saw how important I was to them.   I witnessed the grief of my friend’s family members and could not imagine my family having to face the same fate unnecessarily.   If I could prevent something terrible from happening to me, I would do that not only for myself, but for them as well. Teenagers think they are invincible.   They take risks.   Part of this is just growing up.   I took some risks that could have ended my life, and so did my friends.   Fortunately, I skipped out on that night and made a better choice.   Since that night I have also made better choices and it has improved my life tremendously.   I watch what I do and where I do it.   I am aware of my surroundings at all times.   I reach out to my family and keep in touch with them and let them know that I am OK.   I value my family and their support and love and realize what a special person I am in this world to them.   Because of tragedy, I have become a better person.   My friend’s death still haunts me, but it also keeps me sober and aware of my own precious life.

Categories of Evasion Techniques

Categories of Evasion Techniques Evasion techniques The term evasion technique groups all the methods used by malware to avoid detection, analysis, and understanding. The evasion techniques can be classified into three broad categories, namely, anti-security techniques, anti-sandbox techniques and anti-analyst techniques. Anti-security techniques These techniques are used to avoid detection by antimalware engines, firewalls, application containment, or other tools that protect the environment. Anti-sandbox techniques These techniques are used to detect automatic analysis and avoid engines that report on the behavior of malware. Detecting registry keys, files, or processes related to virtual environments lets malware know if it is running in a sandbox. Anti-analyst techniques These techniques are used to detect and fool malware analysts, for example, by spotting monitoring tools such as Process Explorer or Wireshark, as well as some process-monitoring tricks, packers, or obfuscation to avoid reverse engineering. Some advanced malware samples employ two or three of these techniques together. For example, malware can use a technique like RunPE (which runs another process of itself in memory) to evade antimalware software, a sandbox, or an analyst. Some malware detects a specific registry key related to a virtual environment, allowing the threat to evade an automatic sandbox as well as an analyst attempting to dynamically run the suspected malware binary in a virtual machine. It is important for security researchers to understand these evasion techniques to ensure that security technologies remain viable. Malware detection on mobile devices The basic differences between a PC and mobile device are constrained in terms of computation power, memory and limited battery resources. The targeted exploits of mobile malware are also significantly different from those on PC due to the differences in operating systems and hardware. For e.g. Majority of mobile devices are based on the ARM architecture. Hence, we need to provide due consideration when using the PC based methods for mobile devices. The detection method must use memory and computational resources efficiently and not drain the device battery. The detection method must be cost-efficient to update over the wireless network. There are two general ways of protecting the mobile device. One is to offer protection at the device level and the other is to offer protection at the network level by inspecting packets destined for the device. Device based protection detects and cleans malware including viruses, Trojans and spyware that are installed on the device whereas network based protection looks to detect and prevent intrusions in the network. Malware Analysis Classification All classification approaches taken in the literature can basically be categorized into two types: (i) based on features drawn from an unpacked static version of the executable file and (ii) based on dynamic features of the packed executable file. These approaches are further classified into signature based, behavior based, hybrid based and machine learning based approaches. Signature based approaches are simple and capable to operate online in real time. They detect only known malwares and are not useful for detecting new, unknown and stealthy malwares. They are less powerful with respect to evasion techniques (i.e) obfuscation transformations can easily defeat signature-based detection mechanisms. A signature matching algorithm is well suited for use in mobile device scanning due to its low memory requirements. Behavior based approaches are designed for analyzing the malwares dynamically, thereby allowing it to detect unknown malwares efficiently. They rely on system call sequences/graphs to model a malicious specification/pattern. Behavior-based methods and machine learning methods are dynamic approaches. Anomaly-based approaches, also known as profile-based approaches, profile the statistical features of normal traffic. Any deviation from the profile will be treated as suspicious. They detect previously unknown attacks, but they showed high false-positive ratios when the normal activities are diverse and unpredictable. Specification-based approaches are similar to anomaly detection, but they are based on manually developed specifications that capture legitimate (rather than previously seen) system behaviors. They avoid high false alarm rates caused by legitimate but unseen behavior in the anomaly detection approach. Their drawback lies in more time-consumption as they develop detailed specifications. Thus, one has to trade off specification development effort for increased false negatives (i.e., likelihood that some attacks may be missed). Heuristic approaches for detection in PCs include semantics-based, visualization-based, social network based, entropy based, cryptographic based, difference equation based, kernel based detection approaches. For detection in mobile, immune system-based, memory acquisition-based, suspicious API call patterns, differential fault analysis approach, Intercomponent communications are the approaches that comes under heuristic category. Much research has been conducted on developing automatic malware classification systems using data mining and machine-learning approaches. However, due to various stealth techniques designed by malware authors, most malwares remain undetectable. Organization This paper presents a detailed insight on malware analysis in both the Personal Computer (PC) domain and the mobile domain, based on literature survey done from 1987. First, the various forms of malware and the impact of malware in PC and mobile phones are discussed. Also, their prevalence in most used operating systems such as Windows (for PCs) and Android (for mobile) is focused. Second, the literature survey explaining the contemporary detection approaches are compared with the ancient approaches and their advantages and disadvantages are discussed. Finally, research questions and findings are discussed, giving key ideas for malware researchers to develop a more robust and efficient detection approach, to improve protection and reduce risks, applicable to real-world scenario.

Risk and return Essay Example | Topics and Well Written Essays - 1000 words

Risk and return - Essay Example Risk and return are two inversely correlated concepts. A person or a corporation that is risk adverse will not take chances. Lower risk lead to lower returns and higher risk leads to higher returns. The general rule of higher risk leading to higher returns is not set in stone. One of the problems with higher risk is that it can lead to financial catastrophes. For example imagine a person that invests in a penny stock. Penny stocks are considered the most risky of all types of investments. The person decided to invest in penny stock X because he wanted the possibility of earning a higher return. Due to the risk associated with penny stocks the stock ended up defaulting due to the fact that the company went out of business. In this particular case instead of obtaining a higher return the investor ended up losing all his money. 2. Return on investment can be defined as a performance measure used to evaluate the efficiency or to compare the efficiency of a number of different investments (Investopedia, 2011). The formula to calculate return on investment is (Gain from investment –cost of investment) / cost of investment. Companies are always looking to maximize their return on investment. Corporations able to obtain above normal returns on investment are more profitable than the competition. Return on investment can be manipulated when determining projects by changing the expected return of the company. For example a company may establish new financial policy of only accepting projects that achieve a return on investment of 10%. ... The firm lost approximately $15,000 from this project. To me this experienced proved that higher risk can lead to operating losses. 4. The concept of higher risk leading to higher profits is real and in my personal experience it has paid off dividend. When I took my first finance course the professor gave the class a stock market simulation project. I like the project so much that I decided to turn the project into a reality. I opened up an investment account with Scottrade. I invested $2000 to build up a portfolio of stocks. The portfolio was composed of about six stocks including several blue chip stocks and a penny stock. The penny stock was VTSS. I invested about $350 in the VTSS penny stock. After two months the penny stock when up from $0.35 to over $1.50 cents. I made over $1000 dollars from the purchase of the stock. When the class ended I decided to cash out my portfolio. I utilized the earnings from my portfolio to purchase a 1994 Eclipse automobile for my sister. 5. In the corporate world companies have to take risk in order to obtain a return. A risk that a lot of multinational companies are faced with is the decision to penetrate new marketplaces. There are regions in the world that are susceptible to huge risk such as the Middle East. In the Middle East the risks associated with terrorism are very high especially for American companies. Taking chances is a part of the business process. Even when a company has a successful product line the constant changes in the marketplace forces companies to take risk such as introducing new products into the marketplace 6. People take risk in their regular everyday life without even realizing they are doing it. For example a person

Portrait Of A Dog from FAMILY GUY Essay Example | Topics and Well Written Essays - 750 words

Portrait Of A Dog from FAMILY GUY - Essay Example Producer, writer, MacFarlane tries to portray and explain through this episode how a dog is segregated from society despite being the closest member of a family; he wants to have a major impact on the audience by letting them know how the most loyal member of their families, who might even be the caretaker, is not taken care of and bossed about, like a slave. Upon reaching the dog show, Brian is forced by Peter to behave like the other dogs in order to win; however when Brian refuses because he feels that his dignity is at stake, Peter orders him and shouts at him. This makes Brian feel unwanted and oppressed in a way and puts him in a difficult situation. To support his position, MacFarlane has tried to draw an analogy with respect to most people belonging to society and how they are stereotyped. Then, he talks about exclusion from society for a certain section of people, and finally about how even though they are living beings and have equal rights, are not treated equally in accor dance to the laws that have been laid down, and do not even have a voice which can be heard because of the deafening noise of society in the environment. Just because Brian is a dog does not mean that he has to obey his master by sitting when his masters commands him to, or rolling and heeling when his master orders him to. Brian refuses on the grounds of having his own voice and his own wishes and dreams to fulfil; he does not want to be treated like how the other dogs are treated because he has evolved more than them and is capable of much more than just being a pet and guarding the house; Brian is a true depiction of what kind of a friend a dog can be to a man. Brian however feels unwanted and leaves Peter’s side; Peter’s ego also leaves him to himself, not going to search for the lost dog, despite his wife Lois repeatedly asking him to. In his heart Peter knows that he has made a mistake by stereotyping Brian, however, he does not give in to the fact as soon. MacFa rlane wrote this episode in order to impact his audience so that they would understand how people and animals are stereotyped; for example, when the police find Brian without a leash, they immediately turn him in, when Brian drinks from the public fountain in the park, he is frowned down upon by the other people around him and again taken in by the police as a fugitive for a crime that he has not even committed. All he asks for is to be understood by people properly who do not look at him as a dog, but as a living being with feelings, just the same as other human beings. Furthermore, when he tries to enter a supermarket or a restaurant, he is thrown out just like ‘dogs’ are, just because he is stereotyped to be a dirty and misbehaving animal. Ultimately during the courtroom scene as well, the judges, even though they give Brian a chance to explain his conduct, suddenly change their minds and ask each other â€Å"Why are we listening to a dog?† This comment howeve r hurts the other Griffin family members who by this time have realised the importance of Brian in their family – just because he is a dog does not mean that he needs to be treated like one. If he is willing to expand his intellectual horizons, then he should have the full opportunity to be treated like an equal member of the family. Peter understands that having an equal status and being treated with an equal status of the family are two different things and finally, the Griffins are able to provide the same to Brian. This is how MacFarlane achieves his

TRAINING MANUAL Coursework Example | Topics and Well Written Essays - 750 words

TRAINING MANUAL - Coursework Example This training manual indicates some important aspects that our organization should emulate in order to improve its performance. As indicated by the CEO, the workforce in her organization is under strife. One of the causes of this conflict is lack of diversity. As she notes, the front-line supervisors are white males. This implies that there is diversification since the organization does not allow introduction of new ideas from other races. Another notable issue is age discrimination. The age of stream-line managers makes innovation difficult. This is based on the fact that young employees are productive in nature and have the ability to come up with new ways of doing things. By hiring managers and supervisors from one religion background, it is an indication that the organization is discriminative on the ground of religion Currently, the US population stands at approximately 319 million people. Being the third most populous country in the world, US population is made up of various races which includes white, Hispanic, black and Asians. The white race forms the major part of the population standing at 224 million people which is equivalent to 73% of the whole population. Latino and Hispanic Americans takes 48% of the population. Asian Americans take approximately 5.3% of the population while multiracial Americans are approximately 2.6%. The current trend indicates that the US population will increase at a very high rate based not only in the increase on food production but also due to quality health services that have reduced the rate of child mortality. Notably, the US Asian population has indicated an increasing trend as compared to Asians. For example, in 2013, US Hispanic stood at 54 million people a 2.1% increment from 2012. Despite the reduction in the number of immigrants between 2007 and 2009, the number of foreigners arriving

How does Robert Grave's The naked and the nude (1957) use concrete Essay

How does Robert Grave's The naked and the nude (1957) use concrete diction in order to draw a distinction between the naked and the nude - Essay Example Nevertheless, the heart of the poem is the controversy between the naked and the nude. The first and probably initial meaning of nakedness is anatomical, as in the following synecdoche: "The Hippocratic eye will see In nakedness, anatomy" (ls. 3-4), but the secret meaning of the term is freedom, absence of shame and ignorance of scorn. Nudity, thus, points to the 'social' meaning of nakedness: "deficiency of dress" (4), prohibited and scorned by most people. The nude should be understood as those blaming and judging the naked with religious or moral values: "They grin a mock-religious grin Of scorn at those of naked skin" (17-18). Another meaning of nakedness is therefore the reception of scorn and hatred, addressed to both nudity and nakedness as indecent. When the person is nude, they feel themselves an anatomical pattern, a body, similar to other human bodies of the same gender, whereas nakedness indicates that each body is a unique and exceptional piece of art, as in the followin g metaphor : "And naked shines the Goddess when She mounts her lion among men" (11-12).

Island of stone money Essay Example | Topics and Well Written Essays - 500 words - 1

Island of stone money - Essay Example The uniformity of Fei was another element that added to its qualification as money. As a trait in Fei, the stone could not be duplicated and this helped to restrict the use of alternative commodities as currency. Fei was a viable item for money because it was transportable. It had a hole in the center that helped in carrying it around especially when the need to complete a transaction arises (Friedman 1). The suitability of Fei to perform the function of medium of exchange underpinned its qualification as money. Fei allowed the islanders to transact buying and selling goods amongst themselves conveniently. Money helps in storing value and so did Fei. For example, a family in the Islands was renowned for its wealth because of an ancestor who had discovered a Fei that, besides having sunk in the sea, it still gave them a sense of wealth (Friedman 2). Fei was commodity money because its users accepted it as a form of payment even when they did not have a specific need for it. This is the reason why it was not necessary to carry the Fei from the buyer after completing a transaction. The value in use of Fei is one paramount aspect that justifies that it was commodity money. Fei had intrinsic value and besides helping the buyer to get the goods and services they needed, the seller obtained a sense of wealth and he or she enjoyed the prestige ascribed to people in possession of it. It therefore helped fulfil the goal of an economic activity of acquiring the value of commodities and services. Fei is commodity money because using it in transactions resembles barter trade only that it has a single recognizable unit of exchange (Friedman 2). Fei also qualify as commodity money because it has value in exchange. Exchanging Fei for other goods helped buyers indirectly acquire other items. Fei had value in exchange and if its value in use changed, it would have

Is edcuation a service industry Discuss and critically evauate the Essay

Is edcuation a service industry Discuss and critically evauate the role of the WTO in education - Essay Example Higher education is increasingly seen as a commercial product to be bought and sold like any other commodity. Higher education commercialization has now reached the global marketplace. According to the American Heritage dictionary, the term "EDUCATION" is defined as the knowledge or skill obtained or developed by a learning process (Answers.com). The World Trade Organization (WTO) is considering a series of proposals to include higher education as one of its concerns, ensuring that the import and export of higher education be subject to the complex rules and legal arrangements of the WTO protocols and free of most restrictions. The demand for higher education, on the one side, is growing, while on the other side, trans-border education is increasing. The capacity of the public sector has not kept up with this demand. This coupled with the recent developments of ICTs and the ensuing growth in online learning has resulted in the creation of this very lucrative market. Though higher education has a higher calling, it will not be able to compete successfully for necessary resources unless its rules comply with those established by the World Trade Organization (UNESCO) . ... Let us take a quick look at the history and evolution of education to understand it from various perspectives. Going back to the world's ancient civilizations of Egypt, China, Mesopotamia and Indo-Harappan civilizations, it's amply clear that the knowledgeable and the wise ones of the society were looked up to "educate" others. Coming a little closer to out times, I'm sure we can talk of various philosophers like Socrates, Plato, Seneca, Archimedes etc, who are even today acknowledged as some of the world's greatest thinkers and to make a point were in demand to "educate." At that point there was, strictly speaking, no concept of standardization. Education, especially the primary education has spin offs and major economic, social and financial implications on the society. Some of the economists have gone to the extent of linking primary education with the growth of a country's Gross Domestic Product (GDP) (Economics of Higher Education, 2003). Furthermore, education plays a very critical role in not only shaping an individual's capabilities and competence but also has spin - offs on nations. On inspection of history, one can also fairly conclude that economic growth has happened around the seats of education. Also there was great social differentiation between the educated and the not educated (UNESCO). Massing of wealth by the educated and the depreciation of values, later on, has lead to many social revolts, which is a different story and line of pursuit. By the end of the 19th century, all nations globally had recognized and set up some systems of education essentially aiming at long term growth prospects for themselves ( UNESCO). The burgeoning needs for education driven by governmental support, spurn the parental

The Secular Progressives vs. The Traditionalists Essay Example for Free

The Secular Progressives vs. The Traditionalists Essay In the New York Times best selling book from Fox News Commentator and mediator for The O’Reilly factor, Bill O’Reilly in his book Culture Warrior, defines and separates the two main competitors for the culture of America: The Secular Progressives vs. The Traditionalists. O’Reilly sees this battle as much more important than the more known and easily recognized conservatives vs. liberals and consequently sees the stakes as being that much more important as well with the winner deciding the fate of America policies, both foreign and especially domestic, for generations to come. As a self proclaimed culture warrior, O’Reilly puts himself center stage in this debate as he boasts that he sees himself as one of the most hated men in America as a result of his views on the media and other secular progressives and what he views as their destruction of the core values that has helped to make America great. â€Å"The culture war has also made me perhaps the most controversial broadcaster in the country. That hot-button label controversial gives my enemies, they think, the right to attack me and my enterprises ceaselessly, unfairly, even dementedly. I truly drive the opposing force nuts! As you may know, Im engaged in fighting them on a daily basis, and that warfare is the subject of this book. † ( O’Reilly, 5) And regardless of one’s opinions on Mr. O’Reilly, that is exactly what he does since he points out that one of the most important aspects of being a traditionalist is keeping your word. O’Reilly shows how the culture war has played out in such high profile cases as The Passion of the Christ, Fahrenheit 9/11 and the battle against religion in public life. O’Reilly also touches on race, education, the protection of children, the ACLU and the war against Christmas which according to O’Reilly has seen an escalation in recent years in favor of political correctness which has run out of control. Bill O’Reilly enjoys high ratings and stellar book sales because he pinpoints the moral decline in America that millions of Americans agree is happening in America. At the same time, the name Bill O’Reilly also invokes many an impassioned opinion with many Americans hating what he has to say and according to O’Reilly, have levied death threats against himself and his family for his outspoken views. As someone who has read this book and is well aware of the impact that O’Reilly has on American media, either in an affective way, either positive or negative, the opinions of the author always do invoke a response from individuals. Whatever controversies are the hot topic in the news, O’Reilly fearlessly confronts them and the reader, regardless of his political affiliation, is not left wondering what side of the isle O’Reilly is on. He sees many aspects of life in black and white and is both revered and hated for such beliefs. â€Å"The culture war must be won quickly and definitively, and the best way to do that is to expose the secular-progressive movement in our country for exactly what it is, to explain why it is so harmful for America, and to identify the movements top leaders. So here we go! † ( O’Reilly, 6) O’Reilly, towards the end of the book concedes that this will be a tough fight and that they winner is not set in stone. Therefore, expect more books of the same genre in the future from Bill O’Reilly. In the 200 pages of Culture Warrior, O’Reilly wastes no time in starting his unapologetic attacks on a wide variety of interests in America. â€Å"For a variety of reasons that I will explain, I have chosen to jump into the fray and become a warrior in the vicious culture war that is currently under way in the United States of America. And war is exactly the right term. On one side of the battlefield are the armies of the traditionalists like me, people who believe the United States was well founded and has done enormous good for the world. † (O’Reilly, 10) According to O’Reilly, an example of the influence of the secular progressives’ power and influence in American culture is the war on Christmas perpetuated by the chief of all secular progressives: The ACLU. â€Å"Gradually, Christmas trees did become ‘holiday trees,’ Christmas vacation became winter vacation and Christmas parades became â€Å"Festival of Lights. † (O’Reilly, 45) In America, between 80-85% of its citizens define themselves as Christians. Yet, O’Reilly points out the push by the secular progressives on the country towards a more religiously neutral celebration of the holidays. The word â€Å"Christmas† and â€Å"Merry Christmas† is no longer politically correct to say, but the more neutral â€Å"Happy Holidays. † Christmas trees are being replaced by Holiday trees even though their resemblance is the same. Using the term Christmas to describe the 25th of December as the birth of Jesus, and subsequently, the reason for the celebration is seen as oppressive to the minority in America that do not celebrate Christmas and therefore feel out of place during the Christmas season. On the other side of the isle are the traditionalists who see this as an assault on Christmas and political correctness gone too far and is out of touch with the majority of American in this country. O’Reilly identifies the actions of the secular progressives as efforts to move America into being identified as neutral when it comes to religious issues. In doing so, O’Reilly sees this trend as being in opposition to the motivations of the country’s founding fathers; that, the majority were very religious and their mention of God can frequently be found in their personal writings. O’Reilly outs the ACLU as center stage in his fight against the secular progressives. O’Reilly gives them credit for the lambasting of Christmas, the neutralization of religion in public life and for all sorts of moral degradations in American culture. This fight against the ACLU will not be completed any time soon and will most likely be seen in O’Reilly’s next book to be sure. O’Reilly points out in another example of the ideological differences between the secular progressives and traditionalists are their respective views on government and the desired role that each side wishes would play in their life. â€Å"On the home front in America, traditional forces strongly believe that their hard-earned money is not the property of the government, to be distributed as largesse to others who, perhaps, are not willing to work to earn their prosperity. †( O’Reilly, 75) O’Reilly points to Europe and the stagnation of the economy that many of the nations are enduring. There is little motivation to work and to get ahead in life because of the high level of taxation and the desire of the secular progressives to copy America’s government involvement after that of Europe’s. O’Reilly says that the secular progressives wish to drastically increase taxes and therefore, kill the incentives that many Americans have to be independent and to work for what they have instead of high taxations creating a cradle for people who do not wish to work. O’Reilly wishes to avoid America moving in that direction and that America’s economy remain independent of high taxes which would fund such social programs like handing out clean needles to drug addicts, condoms to students and free money to people who do not wish to work. Such ideas firmly place O’Reilly among the traditionalists of America and that is where he is likely to stay. Among one of O’Reilly’s most impassioned rants he saved towards the end of the book. It is against the people who seem to rant against America and all that is supposed to be wrong with her. In the chapter entitled â€Å"Hating America,† O’Reilly lists the people in the spotlight that seem to do their best to degrade America and the greatness that O’Reilly sees on a daily basis. O’Reilly, who is in opposition to the ideology of Norman Mailer but one who respects him, details the differences in their thinking concerning conservatives vs. liberals and for O’Reilly traditionalists vs. secular progressives and their opinion on America. â€Å"A good example of the useful face-off between polar opposites was my interview with Norma Mailer in March of 2006. One of America’s great writers, mailer doesn’t hate America but he finds it seriously flawed-as you know, a core secular progressive tenet. But mailer separates himself from the S-P garrison because he sees its weaknesses, selfishness and relativism. . . . Mailer says: ‘A great war is going on here, larger even that we realize, between liberals and the conservatives. The conservatives are saying in effect: ‘You guys are trying to wreck existence by becoming too vain, too godless. † And liberals are replying, â€Å"Your obsession that God is judgmental looks to force all of humanity into rigid patterns that won’t work any longer. † (O’Reilly, 120) O’Reilly thinks that Mailer is incorrect but unlike his personal detractors, does so in a respectful manner. â€Å"But Mailer is wrong. Traditional and conservative thinkers who understand their country do not put God at the head of public policy, nor do we point fingers at the opposition and label them sinners. Traditionalists believe that secular-progressive policies will weaken America and lead to societal chaos. While we see no reason to banish God from the public square, we don’t expect Him to be writing social policy on tablets and handing them to us in the Sinai. † ( O’Reilly, 193) O’Reilly does state the importance of the Bible and that it must be on the reading list of every true traditionalist but that a traditionalist will not be zealots in their pursuit of establishing a theocracy in America. In the second phase of secular progressives’ view that America is seriously flawed is their desire for America to no longer be the lone superpower in the world. â€Å"The secular progressive movement wants the United States to decline in power. It wants a new world order where global consensus would rule and the superpower model for our time would recede into obsolescence. †(O’Reilly, 194) But O’Reilly accurately points out a different side towards America’s effect in the world and an effect that is central to traditionalists’ opinion of America and of her greatness. â€Å" By contrast, the T-warrior will fight to keep, even increase America’s vast power. Why? Because T-warriors understand that the United States is a righteous country that has in our brief history freed billions of people from political enslavement. It is our might and money that brought down Tojo, Hitler and the Soviet Union†¦ If we go into decline, the world would be a much more dangerous place. Can you picture Russia and communist China dominating the world? How about the combined Arab states? † (O’Reilly, 194 Journalist as defined by O’Reilly, the answer is a resounding NO! The greatest strength of O’Reilly and the strength that makes him so successful can sometimes be one of his weaknesses: arrogance. Many of his points go beyond liberal or conservative, secularist or conservative but for the others, it might be seen as relative as it depends on the reader to make the final decision since the decline of morals or whether ignoring America’s religious foundations is a good or bad thing may never fully answered in this lifetime and in this country. But such topics are always good for material since millions of Americans do closely follow O’Reilly on the radio and on television. The reader’s view on the Culture Warrior depends upon their religious and political leanings. If one feels that the existence of a liberal media that wishes America’s influence in the world to be curtailed is greatly exaggerated and America’s declining morals either doesn’t exist or is not important, Culture Warrior will evoke a strong and negative response. However, on the other hand, if one defines himself as a conservative and/or traditionalist, then the topics that O’Reilly details will hit its mark. And for millions of Americans, it does just that. This is an important and entertaining book that, like much of what O’Reilly does and says, will spark many needed discussions around the classrooms and water coolers of America. O’Reilly is effective when it comes to seeing and articulating issues of importance in today’s ever changing society and most importantly, it is a window into the mindset of millions of Americans.

Concepts of Ageing and Disability

Concepts of Ageing and Disability Impairment, disability, and handicap Impairment is any loss or abnormality of psychological, physiological or anatomical structure or function e.g. hearing or vision impairment, brain injury, impaired movement, impairment of the sense of smell. Disability is any restriction or lack (resulting from an impairment) of ability to perform an activity in the manner or within the range considered normal for a human being e.g. unable to perform ADL’s, communication, learning and working. Handicap is a disadvantage for a given individual, resulting from an impairment or a disability , that prevents the fulfillment of a role that is considered normal (depending of age, sex and social and cultural factors) for that individual. Similarities and differences: Impairment, disability, and handicap all avoid a person to accomplish normal functions in certain areas of body. The difference is that impairment is the irregularity in structure of function of the body , the condition of being unable to perform as a consequence of physical or mental unfitness such as dysomia- impairment of the sense of smell while disability is the restriction of be short of of ability to perform certain utility. Disability is an umbrella term covering impairment, activity limitations and participation restrictions. Handicap refers to condition that leads to impairment of disability and prevent the person from doing things that other people of their age of gender would normally do, the case is any disadvantage that makes success more difficult or place at a disadvantage such as â€Å"He was handicapped by his injured ankle†. Ageing, old age and ageism Ageing is progressive and universal starting at birth and ending with death. Ageing and disease processes are not the same, the life expectancy in developed countries has increased by more than 30 years in the last century. Also in New Zealand the proportion of older people is expected to grow rapidly over the next 20years. The process of change in the properties of a material occurring over a period, either spontaneously or through deliberate action. Old age: old people often have limited regenerative abilities and are more tend to disease, syndromes, and sickness than younger adults. The elderly also confront other social issues such as retirement, loneliness, and ageism. The chronological age donated as â€Å"old age† varies culturally and historically, so , old age is â€Å"a social construct† rather than a definite â€Å"biological stage â€Å" Ageism: one of the challenges to positive ageing is ageism. Ageism refers to the discrimination that older people can experience due to their age. Often ageism is reflected in eligibility for access to support and resources Also in employment ,(particularly those who experience impairments)are overlooked for employment opportunities. Ageism also occurs when there are negative forms of social exclusion and judgments made about older people on the basis of the perceived worth of their contributions. Similarities and differences: Ageing, old age, and ageism all connect grow older with old person. The difference is that ageing is What’s happening as you get elder through life and old age is the result of aging for a long enough time where you are close to death and your life is coming to an end Ageing is the heaps of thing are changing in a person over time. Ageing is many angles of process such as physical, social, and psychological aspect . While old age is contained in ages closing or exceeding the average life span of human beings, and the life cycle of the end of human beings. Ageism is a combination of three connected components. Among them were prejudicial attitudes towards older people, old age, and the ageing process. Discriminatory approach against elderly, policies that maintain stereotypes about elder people. Theories of ageing in relation to gender, sexuality, race and class The social model of disability : Disability is caused by physical, organizational, and attitudinal barriers in society. Looks for full integration of individuals to society. Focus on social acceptance and equality. Identifies systemic barriers, negative and exclusion by society. Sees society as the contributory factor in disabling people. Psychosocial Theories of Ageing : As people grow older, their behavior changes, their social interactions changes, and the activities in which they engage change. Gender Differences The Social Model of Disability: In osteoarthritis, men and women had significantly difference in pain, pain behavior and physical disability. Women feel pain more seriously than men does. it leads depression to women more than men. It can be barriers in social involving for women. Biological Theories of Ageing: Women have lower cardiovascular risk and greater longevity than men. So some study supposed that there are important gender-related differences in beat-to-beat heart rate dynamics. But some study discovered that heart rate did not be dissimilar between age groups or genders. The heart rate power decreased with age in both men and women. Sexuality The Social Model of Disability : The body of sexuality is at the heart of contemporary political and theoretical issue. Yet the social model of disability makes it a banishment. Sexuality of disability is caused by attitudinal barriers in society. Nevertheless presently old aged sexuality is understood and increasingly accepted in society. Biological Theories of Ageing : Human sexuality is the ability to have erotic experiences and responses. Sexuality can have biological interest and attraction for another person. The biological aspect of sexuality in ageing refers to the reduction of reproductive mechanism as well as the basic biological drive lessen that exists in all species. Race The Social Model of Disability : Data are from population –based sample of 4,136 African American and Whites aged over 65 living in North Carolina. There is reduced risk for disability when they associate with friends as a social interaction occurs. By instrumental support leads to increased risk for disability risk significantly , with a greater adverse effect among Whites than African Americans. Expect for instrumental support, there were few racial differences in the association of social relationships with disability. The Medical Model of Ageing : This study examined surgery for colorectal cancer among medical beneficiaries 65 years of age or older with an initial diagnosis in 1987. White patients were much more likely than Black to undergo surgical resection, even after age, and location and extent of tumor were controlled for. Deprivation The Social Model of Disability : If the disability person has no immediate family or carer to support them , a representative will inform him/her for correct managing. The managing authority at the care home or hospital should work together to ensure this disability person understand the deprivation of liberty process, that he/she knows his/her right, and that they receive the right support when the authorization process starts and a result has been done. Otherwise deprivation of liberty leads them to make barriers in society to them. Psychosocial Theories of Ageing : The elderly grow older , their boundary is restricted by someone who care for them. If you feel that elderly is being deprived of their liberty ,speak to the person in charge. They try to agree on changes that can be made so that the person’s freedom is less restricted. For example, person who with dementia you can’t let them go as a normal person . but should ensure that only deprives someone of their liberty in a safe and correct way, also that is the best interests of the person and there is no other way to look after them. Otherwise their social interactions significantly change to the worst way.

Plasmid Extraction :: essays research papers

Introduction   Ã‚  Ã‚  Ã‚  Ã‚  Chitobiase, from Vibrio harveyi, is a membrane bound lipoprotein involved in the degradation of chitin. Chitobiase is similar to and may share a common ancestry to the a-chain of human b-hexos-aminidase. Chitobiase is encoded by chb.   Ã‚  Ã‚  Ã‚  Ã‚  In this experiment, a restriction map for restriction enzymes Eco R1, Pst1 and Hind III using Southern hybridization and restriction analysis of pRSG 192. pRSG 192 is a recombinant plasmid derived from the chb gene and pUC 19, a 2.7kb engineered plasmid which encodes for ampicillin resistance, a portion of the lac operon and a multiple cloning region . The chb gene exists as a 3.6 kb insert in the mutiple cloning region of pUC 19.   Ã‚  Ã‚  Ã‚  Ã‚  The major goals of Experiment One will be to isolate pRSG 192 from an overnight culture of E. coli, amplify a region of the chb gene using PCR, and to map restriction sites within the chb gene using restriction analysis and Southern hybridization. Methods Plasmid Isolation Four microfuge tubes containing cell pellets representing 3.0ml of cells(2 x 1.5ml) from an overnight culture of E. coli were prepared. The supernatant fluid was discarded and each pellet was resuspended in 150ul of TE buffer(10mM Tris-HCl, pH 8.0; 0.1 EDTA). 300ul of SDS(1% SDS, 0.2 N NaOH) was added to each pellet. The tubes were placed on ice for five minutes, after which, 225ul of ice-cold 3M potassium acetate(pH 4.8) was added. The tubes were again placed on ice for five minutes and subsequently microfuged for five minutes. The supernatants were recovered and transferred to new tubes. One volume of phenol/chloroform was added to each new tube. The tubes were shaken vigorously for two minutes and centrifuged for five minutes. The upper, aqueous phase was recovered and transferred to a new tube. One volume of chloroform was added to each tube. The tubes were vigorously mixed and microfuged for three minutes.

Effect Of Postimpressionists On The Next Generation Essay -- essays re

Postimpressionism Postimpressionism was a movement in late-19th-century French painting that emphasized the artist's personal response to a subject. Postimpressionism takes its name from an art movement that immediately preceded it: Impressionism. But whereas impressionist painters concentrated on the depiction of a subject's immediate appearance, postimpressionists focused on emotional or spiritual meanings that the subject might convey. Although impressionist artists interpreted what they saw, their approach nevertheless remained rooted in observation of the natural world. Postimpressionists conveyed their personal responses to the world around them through the use of strong, unnatural colors and exaggeration or slight distortion of forms. Postimpressionism can be said to have begun in 1886, the year that French painter Georges Seurat exhibited Sunday Afternoon on the Island of La Grande Jatte (1884-1886), and to have ended in 1906, the year French painter Paul CÃ ©zanne died. British art critic Roger Fry, however, coined the term postimpressionism, in 1910 when he organized an exhibition of French paintings at the Grafton Galleries in London. Fry is said to have been dissuaded from using the word expressionist to describe the work of CÃ ©zanne, Seurat, Paul Gauguin, Henri Matisse, Vincent van Gogh, and others, and to have finally declared: "Oh, let's just call them post-impressionists; at any rate, they came after the impressionists." The term was firmly established when Fry held a second show of postimpressionist art at the Grafton Galleries in 1912. The Postimpressionists The painters most closely associated with postimpressionism all took part in Fry's first exhibition: CÃ ©zanne, Seurat, Gauguin, Matisse, and van Gogh. Although their styles differed greatly from one another, these artists shared an ability to communicate concepts, emotions, or personal sensation through their art. Unlike other postimpressionists, Paul CÃ ©zanne did not create symbolic equivalents between elements of his paintings and particular emotions or concepts. Instead, CÃ ©zanne, who began his career as an impressionist, felt that he could communicate the intensity of his personal sensation through his painted observations of nature. He repeatedly turned to traditional artistic subjects, such as landscapes, still lifes, and nude bathers. However, his r... ...m, used more decorative shapes, stencilling, collage, and brighter colors. It was then that artists such as Picasso and Braque started to use pieces of cut-up newspaper in their paintings. An early 20th-century school of painting and sculpture in which the subject matter is portrayed by geometric forms without realistic detail, stressing abstract form at the expense of other pictorial elements largely by use of intersecting often transparent cubes and cones. CÃ ©zanne influenced cubism, the highly influential visual arts style of the 20th century that was created principally by Picasso and Braque in Paris between 1907 and 1914. The Cubist style emphasized the flat, two-dimensional surface of the picture plane, rejecting the traditional techniques of perspective, foreshortening, modeling, and chiaroscuro and refuting time-honoured theories of art as the imitation of nature. Cubist painters were not bound to copying form, texture, colour, and space; instead, they presented a new reality in paintings that depicted radically fragmented objects, whose several sides were seen simultaneously. this has been collected from various resources on the net ... ibiblio.org, among others

Within-Class Ability Grouping Essay -- Essays Papers

Within-Class Ability Grouping As a future educator ability grouping is more than likely going to be a part of my classroom. I think it can and will be a valuable tool in effectively teaching all students of varying abilities. Ability grouping is a greatly debated area in the field of education. Opponents to the practice believe ability grouping is detrimental to learning and student self-esteem, but ability grouping, specifically within-class ability grouping, can be very effective in teaching children. The students are able to learn at a pace that is suitable to their individual abilities and teachers are able to construct lessons that are specifically geared towards each level. Within-class ability grouping necessitates flexibility and frequent interactions between student and teacher to determine whether or not the child is in the proper group. In ability grouping the "high achievers benefit from having to compete with one another" (Hollifield, ERIC database). The low achievers in a group of children of simila r level feel more comfortable and are, therefore, more willing to participate. Children should not be put into groups in every subject area, but rather in a few areas where grouping has proven beneficial. "Low-achieving students seem to learn more in heterogeneous math classes, while high and average achieving students suffer achievement losses—and their combined losses outweigh the low achievers’ gains" (Loveless, internet). Regrouping for mathematics and reading has proven effective. The students are in heterogeneous groups for most of the day, but then are grouped according to level for those two subjects. "Results indicate that regrouping for reading or mathematics can improve student achievement. However, the l... ...teacher Mrs. Petrigala: November 17, 2000; Michael’s first grade teacher Joshua Hammond: November 22, 2000; 10 year old son Sara Hammond: November 22, 2000; 12 year old daughter Works Cited Goldberg, Miriam L., Joseph Justman, and A. Harry Passow. The Effects of Ability Grouping. New York: Teachers College Press, 1966. Hollifield, John. "Ability Grouping in Elementary Schools." [online]. Http://ericae.net/edo/ED290542.htm. Lou, Yiping, et al. "Within-Class Ability Grouping: A Meta-Analysis." Review of Education Journal 66 (1996): 423-458. Loveless, Tom. "The Tracking and Ability Grouping Debate." [online]. Http://www.edexcellence.net/library/track.html#anchor393575. Slavin, Robert. "Ability Grouping and Student Achievement in Elementary Schools: A Best Evidence Synthesis." Review of Educational Research 57 (1987): 293-336.

On-the-Job Training Essay

Nothing beats experience as the perfect learning tool. This On-the-Job Training served as my stepping stone to purse my dream to be a professional someday. This training gave me an inspiration to be more serious focused in studying. I was encouraged to do more efforts in my studies. Since I was given some ideas about work of an F&B in the company where I conducted my training, I am inspired to be like them someday. Despite the short period of my training, it was still a very meaningful one. The training enriched my confidence created a foundation of being a good employee someday. It caused a very huge effect to me as Bachelor of Science in Hotel and Restaurant Student. I was really renewed. I learned to be diplomatic in both action and words. This training made me realize that it is really good to know what you’re doing and love it. As a student, what I can do for now is to learn whatever I can in school, be inspired, love the path I am taking, and do my best in everything I do, with a positive outlook in mind. I realized that I should be more focused in school and do everything heartily and with all that I can. It is also very warm to the heart to know that you have accomplished something and even warmer when there are people who are so proud of what you have done and I felt this feeling during my On-the-Job Training. Read more:  Essay About OJT Experience It inspired me to be more determined and competitive in everything that I do in my daily life as a student today and as a professional someday. My On-the-Job Training is very helpful and will be very helpful to me as I continue to take my journey as a fourth year student in the field of Hotel and Restaurant Management. It really gave me a taste of the real world – a glimpse of what lies ahead after I graduate. RECOMMENDATION ACKNOWLEDGEMENT With deepest gratitude and appreciation, I humbly give thanks to the people who, with all they can, helped me in making my On-the-Job Training a  possible one. To my mother, for her unending love and support, for providing all my needs financially and morally, for her patience and understanding during my tiring day that I can’t help her in the chores, for her never fading advices and for being there for me no matter what. To my brother and sister and my best friend who serve as an inspiration to me, who keep on encouraging me to always make the out of everything and for their being proud and ever supporting siblings to me. To the institution where I am studying, Far Eastern University (Manila), where I am continuously growing as a Bachelor of Science in Hotel and Restaurant Student and to —– and family for giving us, students, the opportunity to be educated without spending too much. To all my professors who shared and continuously sharing their knowledge with students like me and keep on molding me into a better person. I am extending my warmest thanks especially to Prof. Elacion who, with all that she can, share with us everything she knows and keep on inspiring me to pursue my goals in life, most of all, my goal to be a professional someday. I thank her for her patience during the times that we commit failures and a big thanks for touching my life and motivating me to study harder for me to have a better future. To the Sofitel Philippine Plaza Manila – F&B Department (Spiral), for their warm welcome to me. To my training Manager, Sir Henry, to my training supervisor, Ms/Mr – And to the rest of the F&B Department, I am very grateful for having them as part of my On-the-Job Training. For all their advices and for everything that they taught me during my stay with them and most of all, for the memories we’ve shared – the happy moments, the sorrowful ones, the rush hours, the brainstorming and during the times that we commit failures and a nerve-wracking days and for everything that they did that contributed to my growth as a human being. I thanks them so much. To my friends and co-trainees, for the happiness and for being there to support me and to comfort me whenever I have difficulties during my training. I thank them for the friendship and teamwork and for being my companions whom I can share my laughter and sorrows with. Above all, to our Almighty God, for his unconditional love and for all the blessing He is showering upon me each day of my life. With love and gratitude, I thank Him for guiding me during my training and for making this On-the-Job Training as possible one. For the provision and wisdom He has bestowed upon me, for keeping me and my love ones always safe, for giving me enough knowledge and ability to perform each task that was assigned to me for the challenges He has given me that made me stronger than ever. I thanks Him for His comfort during the times that I am about to give up. By His grace, I was able to finish this training without any conflict. Most of all, I thank Him for His Word that keeps on reminding me that â€Å"I can do all things through Christ which strengthened me.† (KJV) (Phil. 4:13)

J.B Priestley and his audience Essay

J.B Priestley is someone who has seen enough of the world to make his own judgments. Therefore he has written this play â€Å"An Inspector Calls† to get these views of his across to the rest of the audience. He believes in socialism and doesn’t support the view of capitalism. He tries to promote socialism and show capitalism as an act of egotism. The two main views of society he has portrayed and contrasted capitalists and socialist. We know this through characters of the book to begin with I will look at Mr. Birling as a capitalist. This character was shown to be a very arrogant and proud man. He believed he had more authority and rights than/over everyone else. He is ‘Self made man’. His objectives of life are to make money, and profit for himself, â€Å"It’s my duty to keep labour costs down†. Money for him isn’t an issue. It’s an important part of his life. Even in situations like the sort he finds his image essential. ‘Look, inspector – I’d give thousands’ Mr. Birling can seem to be hollow at times in the sense that he doesn’t always perform in the way he portrays himself to his surroundings. He finds a reason to believe that the inspector’s onset maybe a hoax, He than begins to proceed as though the inspectors arrival had no effect on him. But as soon as the phone rings he begins to panic. Mr. Birling doesn’t like to argue. He is optimistic about the future yet we know what he predicts will not come true. ‘The worlds developing so fast it’ll make war impossible†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.’ And ‘The Titanic†¦. unsinkable absolutely  unsinkable’. The inspector’s comment to Mrs. Birling about young people – ‘They’re more Impressionable’ (pg 30) – adds weight to our feelings that the older generation is Fixed in its attitudes and that if society is to become more caring it will have to be through the efforts of the younger generation. The inspector is just someone who is making the characters in the play realise what they are doing wrong in life, not to cause havoc. This is shown when Sheila ( Mr Birling’s daughter) takes the blame of Eva Smith’s death [http://www.youtube.com/watch?v=bA9lpcBIiL8] all on to her own accord, the inspector assures her and asks her to stay and listen to Gerald’s (Sheila’s fiancà ©) part of the story, so she doesn’t feel herself entirely to blame. Sheila is an example of a capitalist who has realised her mistakes, owned up to them and is prepared to adjust her life after the events taken place in the dining hall that afternoon. She is very intelligent but spoilt. She is naà ¯ve and is very distressed by the news of Eva’s death caused by stress which drove her to committing suicide. She thinks that her father’s behaviour was unacceptable. She readily agrees that she behaved very badly and insists that she never meant the girl any harm. ‘I’ll never ever do it to anybody again’ Sheila had gotten used to the fact of going into a shop and behaving in such a cruel manner, and get somebody (Eva Smith) permanently excluded from their job just because of jealousy, how self-centered of her. Now after somebody  had made her see her mistakes she decided her actions were not acceptable, and this sort of approach to life is intolerable. J.B Priestley wanted to show that there are people out there who haven’t recognised their error’s in life and that maybe this play will help them to do just that. Priestley shows just how wrong capitalism is that it can even lead to death of innocent citizens. So this means there is chance of another war, if capitalism isn’t erased from this world. He shows that people are out there who predict the future like Mr Birling and say things like ‘the Titanic is unsinkable†¦ and the world’s developing so fast it’ll make war impossible’, we know that these predictions made were wrong. But who are we to say that there won’t be another war. It makes you think what might happen In the future if entrepreneurship isn’t stopped, doesn’t it? This is what Priestley wanted, his capitalist audience to feel guilty, and wanting to change themselves for the better. Mr Birling represents Priestley’s hatred of businessmen who are only interested in making money. He (Birling) will never alter his ways and it is left to the younger generation to learn from their mistakes. Mr Birling’s family may seem cheerful, but if you inspect them internally you’ll notice how ruined their family really is. Mr Birling has feelings of guilt but doesn’t show them because of his bold image he has to keep up with, ‘We hard headed businessmen’ He is hurt by the fact that when his son Eric (an alcoholic), was in trouble (with Eva and the money problem he had) he didn’t approach his father with this problem and ask for help, like any other son would have done. This makes Mr Birling upset and angry. ‘You damned fool – why didn’t you come to me when you found yourself in this mess?’ Eric is bad-mannered and coarse towards his father and makes him feel as though they never had a father and son relationship. ‘Because you’re not the kind of chap a man Could turn to when he’s in trouble’. Priestley also shows that money can’t buy happiness. Mr Birling has all the money but does he enjoy time with his family? Is his family falling apart?And is it his entire fault? Capitalism also has this effect on people, that it can tear families apart just as it’s done to The Birling’s. Inspector Goole’s final speech is J.B Priestley’s personal opinion which is that he is concerned that there are many people like Eva Smith who are poor and their lives depend on the way we deal with daily life. ‘One Eva Smith has gone-but there are millions and  millions of Eva Smith’s and John Smith’s still  left with us ‘. The reason for capitalism is people like Mr Birling who have no sympathy for others and don’t care about the rest of the world or poverty; they only care about money and image this is why capitalism and wars are still going on today. If there was more socialism there would be peace. This is J.B Priestley’s major motive of writing this play ‘An Inspector Calls’ is to promote socialism. (Which I hope he has)

Essay On Political Parties In India Essay

Posted in National Issues of India by Vijay Jaiswal On August 29, 2013. No comments In a modern democratic political system of India, with governments based on Parliamentary model, political parties are central to the working of the political system. Political parties in Indian Democracy grow up the as spokesman of organized interests. Thus a Political party system in India is an organization of like minded people based together either to preserve and promote group interests or to promote a particular ideology. Usually every party seeks to promote some particular interest and ideology. The political party constantly seeks to capture governmental powers to secure its ends. In a democracy, the party gets into power through elections. In a Parliamentary system such of India, the political party winning the majority of seats in the Lower House of the Parliament forms the Government, while the Party or Parties failing to get the majority constitutes the opposition. Thus the Parliamentary government is always a Party government. It may be the government of a single party or it may be the government of a coalition of parties. The nature of political party system in India was characterized by Morris Jhones as a dominant one party system. It means that India basically has a multi-party system but one among the many parties is dominant party and monopolizes governmental power. Since independence up to the 4th general election in 1947 this was precisely the picture. The Congress party was in power during all the twenty years from 1947-67 both at the centre and in the states with a brief exception in Kerala in 1958. The 1967 elections saw the fall of the Congress monopoly in several states where unstable coalitions were established. The sixth General Election in 1977 witnessed the fall of the Congress at the centre. The Janata Government was established. But the Janata experiment soon failed. For Janata was in reality an unstable coalition. The Congress gained back its power in 1980. Then there was a B.J.P. coalition government at the centre and in few states. On the basis of their influence and aspirations, parties in India fall into two categories: All India politicalparties and regional political parties. Thus the Congress (I) or the Jananta Dal or the Bharatiya Janata Party (BJP) – are truly All India parties having some sort of influence throughout India and having All India aspirations. There are some other political parties which are professedly All India parties but their influence is limited to particular regions. They may be classed us regional parties with All India aspirations. The Communist Party of India (Marxist), the Communist Party of India, the Forward Block, the Revolutionary Socialist Party (R.S.P) etc. fall into this category. The influence of the C.P.I. (M) for example is concentrated in West Bengal, Kerala and Tripura. The regional political parties are those which are frankly regional in their aspirations emphasizing their ethnic or linguistic identities. The D.M.K. or the A.I.A.D.M.K. in Tamil Nadu, the Telugu Desham in Andhra, and the A.G.P. in Assam or the National Conference in Jammu and Kashmir fall into this category. There are also some frankly communal parties like the Shib Sena emphasizing their religious identity. On the basis of ideology, Indian parties may be classified into conservative, liberal democratic and revolutionary parties. The B.J.P. for example is a conservative party. The Janata Dal and the Congress are liberal democratic parties. The Communist Parties, the Revolutionary Socialist Party etc. are revolutionary parties seeking restructuring of the society along Marxian Lines, while the B.J.P. may be said to occupy the extreme right position in the political spectrum, the Congress, the Janata Dal stand at the centre while the Communist Parties and  the R.S.P. occupy the extreme left position.

10 Point of “The Devil Wears Prada” (Film) Essay

The Devil Wears Prada  is a 2006  comedy-drama film, a loose  screen adaptation  of  Weinberger’s 2003novel of the same name. It stars  Anne Hathaway  as Andrea Sachs, a college graduate who goes to New York City and gets a job as a co-assistant to powerful  fashion magazine editor  Miranda Priestly, played by  Meryl Strep.  Emily Blunt  and  Stanley Tucci  co-star, as co-assistant Emily Charlton, and Art Director Nigel, respectively. 1. The devil wears Prada means that the devil can come in any form and not just the ugly scary version we all expect. He can come as a well dressed good looking person and fool anybody into doing whatever he wants. 2. Prada is an upscale clothing designer. Apparently, she is a difficult person. Therefore, Ann Winter (The Devil) wears Prada clothing. 3. The Devil Wears Prada is two films in one: a caustic, energetic satire of the fashion world and a cautionary melodrama. 4. An ironic measure of the film’s research into the fashion-magazine scene is the fact that there’s almost no journalism in it. 5. Fashion is designed to have you buy something that has the predetermined shelf life of cottage cheese. 6. That a designer will put a fashion combination on a cover of a magazine that you would never dream of coupling together. 7. That people can pay all too much money for a handbag – after all it is just something to put â€Å"stuff† into. Well, just think of a purse is another opportunity to be mismatched with your shoes. 8. Real women will die wearing high heals that are high enough to give you a nose bleed. 9. Even designers have off days, and seasons for that matter. Learn how to just walk away from anything you can’t describe what color it is. 10. I believe that one of Hathaway’s dresses could best be described as the color of thawing frozen spinach.

Critical Thinking questions Essay Example | Topics and Well Written Essays - 750 words

Critical Thinking questions - Essay Example Financial accounting and managerial accounting basically have the same function but their end results are different. The main difference between the two is that financial accounting is conducted and processed so that information can be made available to third parties that are outside the organization. These reports are basically created over a half yearly or annual period and they are reviewed as per the fiscal year. Managerial accounting is more centered towards decisions that have to be made within an organization. The data and information procured during this process is used by the managers of a business or company. The reports that are created under managerial accounting are for a shorter period of time for example a week, a month or even everyday. Financial reports are used by people who may want to invest in the firm or sell the stocks or shares, where as managerial reports are needed for the smooth running of the firm. Financial risk and financial return can be called siblings in a sense. When an investor is putting capital or money into stocks, bonds or generally putting money into a firm he is taking a considerable risk because there is always a chance that he may lose the money that he has invested. Financial return on the other hand is the profit that the same investor would get from his investment. The amount or significance of the return is dependent on the risk i.e. the lower the risk taken, the lower the return will be and the higher the risk taken the higher the return would be. There is always a potential for higher returns based on the risk being a success or failure, if it results in a failure then there will be no returns. The U.S. health care system is made complex by the different types of networks that are created around providers, payers and patients. Pharmacists may play an important role; however, this role is interlinked with many other professionals. â€Å"Pharmacists are intertwined into a web of

Strategic Human Resource Management Essay Example | Topics and Well Written Essays - 2500 words

Strategic Human Resource Management - Essay Example It is important to note that it is difficult to have a consistent HRM approach in the presence of workforce representing multiple demographic segments as compared to earlier uniform workforce. This periodic and apparently long-term change requires management to have flexibility in its practices in order to maintain a positive psychological contract with a diversified workforce comprising of people from different cultures, ages and genders. Therefore, it is essential to determine if SHRM approach and flexibility in its practices can present employers with effective and desired outcomes. Since there are multiple forms of flexible practices used by employers, it is also important to identify likely consequences of these flexible approaches in the light of SHRM. Hence, SHRM advocates integrating HRM functions and organisational goals in order to respond to requirements of external environment. Four major forms of flexibility offered by SHRM are changes in employment models of wage, funct ion, numerical status i.e. contracts, and temporal state i.e. number and patterns of hours worked (Kalleberg, 2001). Different Forms of Flexibility There are various forms of flexible approach that govern current ideology of strategic human resource management. These flexible approaches entail practices regarding workplace, scheduling and compensation. Although a general perception of flexible HRM approach is viewed as employees working from remote locations however it is a more extensive phenomenon than that as not every job can be handled remotely. The term flexibility itself refers to organisation’s ability of adjusting its workforce numerically, functionally and financially in response to external environment and employees’ needs with reference to structure of the business (Wu, 2010, pp. 278-9). The concept of ‘flexible firm’ provided by Atkinson (1985) acts as a foundation behind workplace flexibility and its relation to strategic human resource manag ement. A flexible firm or employer is able to change number of employees according to its needs and also alter source of acquiring potential talent i.e. permanent or temporary hiring, outsourcing or part-time/ remote work arrangements. Another major area concerning flexibility offered by SHRM is the alteration in organisational structure followed by work design. As organizations have transformed into humanistic employers, their organisational model has become more decentralised with reduced bureaucracy. Reduction in levels of management has made employees more accountable and participative in organisational decision making (Armstrong, 2009). Another important element of ensuring flexibility in organisational practices is training employees with reference to external environment. Updating organisational skills’ base is essential for acquiring necessary competitive edge over other firms. The concept of upgrading is also supported by Armstrong (2008) as he has considered adaptat ion to be an important element of employer’s flexibility and adoption of SHRM as a fundamental ideology. Armstrong (2008) and Purcell (2001) have further presented three concepts i.e. resource-based view, strategic fit and strategic flexibility to be the foundation of strategic human resource management which is also supported by Wei (2006).

Argument Paper on Gay Marriage Essay Example | Topics and Well Written Essays - 1000 words

Argument Paper on Gay Marriage - Essay Example Gay marriage should not be allowed because it is unnatural, does not provide a child with both a mother and father, and does not fall under the jurisdiction of the government. Also, a counter argument will be given to the view that not allowing gay marriage is discriminatory. Marriage has always been thought of as between one man and one woman. The reason for this is simple—the main objective of marriage is to continue the human race. Gay people cannot make a child together because it is not physically possible. Of course, gay couples can adopt children or use a surrogate, but this is not the same as producing a child themselves. There is a reason why only one man and one woman can make a baby, and that is because they have the necessary means to do so. A man and a woman getting married further cements their relationship and helps confirm to their children that they will remain committed to one another for a very long time. Gay couples cannot have children together, so there i s no reason to allow them to marry. They should be thought of along the same lines as a heterosexual couple who choose to have a fling. They do not want to have a child together, and that is why they do not get married. Gay people should be able to act in the same way, but demanding marriage is going too far. How a child is brought up plays a significant role in how they act when they become adults. Parents have the greatest single influence over a child because they have the most to do with them. While it cannot be denied that having two parents is better than one, it can also be argued that having a parent of each gender helps a child to grow more. Recent research has shown that â€Å"fathers make some unique contributions† in their children’s lives (Eggebeen). Each gender has certain qualities that they can offer a child, and a child should benefit from all of these qualities rather than just one set of them. Two fathers or two mothers cannot fulfill a child’ s emotional needs because there will always be something missing. This is not to say that gay parents don’t try hard, it’s just that two parents of the same gender can only offer so much. Having parents of different genders means that one parent will make up for where the other one lacks and vice-versa. There has always been fierce debate among many religions over their different points of view, but one thing that nearly every major world religion can agree on is that gay marriage should be prohibited. The reason why virtually every religion believes this is because marriage is something that was invented long before any government came around. Thus, it should not be up to the government to decide who can and cannot get married; marriage is a religious institution. Senator Jim DeMint says that â€Å"the government [is] legitimizing and promoting behavior that culturally we have always considered wrong† (Mantyla). Besides being a religious institution, marriage i s also a cultural institution. It is true that culture is something that can evolve over time, but the concept of marriage has been set in stone for many thousands of years, and there is no reason to change that now. For the government to claim ownership of marriage, it would have to prove that it invented the institution of marriage. However, it did not. The only thing that the government does is legally recognize marriages so as to offer tax breaks and provide

Critical analysis of I heard a fly buzz; Wounded deer; and From cocoon Research Paper

Critical analysis of I heard a fly buzz; Wounded deer; and From cocoon forth a butterfly by Emily Dickinson - Research Paper Example Her concern with these problems and the expressions of her judgement that she has made in her own highly individualistic idiom has probably led to the classification of much of her poetry as mystical. (Humiliata, 144) The work and life of Emily Dickinson became known to the world after her death. She led a secluded life and her work is shaped by her individualistic thinking. She mostly concerns herself with themes of: life, death, material and immaterial things, particularly in ‘I heard a Fly buzz’; ‘Wounded deer’; and ‘From cocoon forth a butterfly’. The running them in ‘I heard a fly buzz’ is death and the momentous experience during the final breaths of life. It is an experience of dying and feeling the last remnants of life. Life is associated with the buzzing sound of a fly- a minute living object. Though everything is still around her; yet it feels as if she is surrounded by a storm. The buzzing sound of the fly is contrasted with â€Å"heaves of storm† (4). Dickinson employs contrast to enhance the various themes in her poetry. The fly is moving while everything else in the room is still. She doesn’t personify the persons present around her deathbed but focuses on their emotions of grief. She does so purposefully so she could heighten the effect of the revelation of the king in power. ‘King’ could be anything- Christian God, or Death.... Even if life is trivial with respect to death or transcendental- it doesn’t let go that easily. The poet can feel life till the last moment. In the last stanza, she symbolizes light as life and darkness as death and the transcendence from light to darkness is gradual and painless. The poet is preoccupied with themes of life and death in this poem. â€Å"Death was important to Emily Dickenson. Out of some one thousand and seven hundred poems, perhaps some ‘five to six hundred’ are concerned with the theme of death...† (Nesteruk, 25-43) The first line of the poem startles the reader: ‘I heard a fly buzz when I died;† (1) because this statement apparently doesn’t make sense (no one can feel anything once dead). But the idea behind this is to elucidate the strong connection of life that a person experiences till the last moment. This poem is about feeling that moment where life and death intercede. Death is associated with power, stillness, a nd darkness. Sound and pictorial imagery is handled very delicately in this poem. The phrase ‘see to see’ is also the culmination of the poem’s complex sound play. It echoes the repetition of ‘stillness’ in stanza 1, and it is the last of the series of sibilants, or hissing sounds (s, sh, z) that run through the poem, building up to the Fly’s ‘buzz’... ... While there are those who see fly as a statement of nihilism that ridicules the notion that death is transcendence, others see the image as more ambiguous. For all its mindless uncertainty, the fly is a symbol of blind, persistent life, and as such, worth clinging to until the very final instant of consciousness. (Leiter, 104) ‘A wounded deer’ is a narrative of a hunter that explains to the poet how a wounded deer behaves when

Reading response Essay Example | Topics and Well Written Essays - 250 words - 25

Reading response - Essay Example Likewise, Hitler understood propaganda as the best medicine to have the masses embrace a particular ideology. Instead of having intellectual propaganda that could only be understood by the intellectually gifted, Hitler believed that the masses are gullible and any effective propaganda had to be in its simplest possible form. However, such propaganda had to have a few, but strong slogans that evoked emotions among the public to elicit the required reactions. Considering the public has limited understanding and would not digest too many materials, Hitler maintained in using a few scale but emotions-evoking points as the best tool for propaganda but with great effectiveness in swaying the public. There have been some cases of propaganda in the United States most of which are related to its foreign ideologies and warfare. For example, a general propaganda was used to justify attacking and dethroning Saddam Hussein from power on the pretext that he had weapons of mass destruction which posed a high risk not only to American citizens, but also to the whole world. Spreading the propaganda created fear attracted support for the U.S and her allies to attack Iraq though nothing of the weapons as claimed was found. Similar propaganda are spread about the possibility of terrorist attacks within American territory to ensure everyone is vigilant in guaranteeing home

Supply Chain Management Case Study Example | Topics and Well Written Essays - 250 words - 1

Supply Chain Management - Case Study Example Another model of picking location is mixed fulfilment model, which enable customers to order directly and the orders will being dispatched from warehouse as well as supermarkets. This method is regarded to be highly flexible but this method is difficult to schedule by the company (Ody, 2000). The customers of Sainsbury’s are involved with both the method of business to pick the ordered goods on time of delivery from picking centres or supermarkets or warehouse. At times, home delivery approach is also scheduled by the companies for high convenience of customers. However, such approach of distribution and delivery is regarded to be difficult as customer when customer is not available. This situation mainly happens when the ordered goods reach quickly or earlier than pre-defined time at pre-defined location. On the other hand, customers pick the ordered goods directly from regional picking centres and warehouses or supermarkets. These were regarded to the distribution centres for company (Ody, 2000). The Sainsbury’s business utilises the ‘orderline’ technology to run its standalone operations efficiently. However, in the current scenario, for high business expansion as well as sustainability Sainsbury’s needed to incorporate a new IT system within its existing system. To integrate such new technology within the old but will take five years’ time to establish the same. Additionally, the company developed website to stay connected with its customers and assimilated a loyal customer base for better future prospective (Ody,

A Nation of Drunkards Assignment Example | Topics and Well Written Essays - 250 words

A Nation of Drunkards - Assignment Example It is evidently clear from the discussion that the White Southerners feared that drinking would turn their Black neighbors into criminals. This drinking according to the temperance reformers created anger and sorrow, which eventually resulted in the destruction of many families and marriages. In other words, the drunkards out of anger and sorrow mistreated their wives and children. Burns and Novick imply that drinking was considered a symbol of masculinity and yet again it often ruined masculinity’s key obligation and expectations, which is an individual’s capability to provide support to their family. In addition, the National Prohibition depicted a coincidence resulting from a combination of certain aspects. These aspects included the Anti-Saloon League’s political skill, and the formulation and implementation of an amendment to the constitution of the federal government, which resulted to the formation of an income tax (ensuring that drink taxes were rendered inappropriate). It also included the entrance of the American nation into the world war one, a factor that led to the demonization of the German-American brewers. Generally, these explanations made by Burns and Novick are the factors that led to the assumptions that the National Prohibition had a high probability of being self-enforcing.

The Extinction of Baiji Essay Example for Free

The Extinction of Baiji Essay The Baiji, also known as the Chinese River Dolphin, are part of the family Plantanistiade, the river dolphin family. They had exsited in the Yangtze River in China for thousand of years. Nevertheless, the Baiji was recently declared extinct. The baiji’s demise can be attributed to over fishing, its lethal environment and the Great Leap Forward in China. Excessive and illegal fishing was a great threat to the baiji’s way of life. Electric fishing and the fishing method called â€Å"rolling hooks† were been banned in China. However, fishermen on the Yangtze River still use them out of convenience, and enforcement of the ban was difficult. The expert Zhou states, â€Å"This (electic) fishing method, in which an under waterdevice is used to stun aquatic animals, kills any organism induding what was once the dolphin’s prey.† 40 percent of Dolphins deaths were due to this kind of fishing annually (Gerg Ruland). In addition, rolling hooks, â€Å"long, braided lines with numerous sharp hooks are meant to catch fish, caused a number of baiji death.† As long as the baiji was caught by one of the hooks, it would struggle with more rolling hooks. Finally, the blood flew out of the baiji’s body, and it would die. (Requiem for a Freashwater Dolphin) . The environment in the Yangtze River, where the baiji had settled its habitat in, was fatal to the baiji. Traffic on the Yangtza River, which is the busiest in the world, damaged the audition of the baiji. Lovgren in his article states that, â€Å"The large-ship traffic on the Yangtze, one of the world’s busiest waterways, confounds the sonic wave that the nearly blind dolphin used to depend on to find food.† Moreover, the boats on the Yangtze attracted a number of the baiji to collide with propellers, since the propellers produced much of the sound wave and confused the baiji’s audition (Ruland). Another assignable cause that destroyed the baiji’s habitat was dams along the Yangtze River. Thes dams further destroyed the ecology of the river. And when the biggest dam, the Three Gorges Hydroelectric Dam in 1994, began to be constructed, this â€Å"wreaked havoc on the baiji’s remaining habitat. In 1997, only 13 baiji remained† (The Tragedy of the Yangtze River Dolphin). People take the big advantage of the valuable nature resources, living near by the Yangtze. However, because of the intemperate use, the baiji could not survive in the perishing environment and finally die. However, neither Chinese people nor the Chinese government kept the protection of the species in mind during the time period of the Great Leap Forward, which was the time to change China into a modern, industrialized communist society. The baiji’s population declined dramatically at the time. The baiji was denounced for their historical status, â€Å"Goddess of the Yangtze River† (Smith, et al). As a result people were encouraged to kill the baiji, since the story of this species was regarded as a part of superstition and feudalism. The baiji also killed for their white skin and flesh(Smith, et al) . It was encouraged for the contemporary to kill the baiji, since they treat baiji as their profit and the symbol of the bad traditional influence. In conclusion, the extinction of the baiji resulted from human activities. People who live near by the Yangtze improved their live depended on the destroying the baiji’s habitat and capturing the baiji. The tragedy of the baiji’s extinction came at a price while the living standard of people was promoted.

Ap Bio Diseases Research Essay Example for Free

Ap Bio Diseases Research Essay 1. Norm of reaction: the phenotypic range that a genotype is associated with due to environmental influences. 2. Multifactorial: characters that have many factors, both genetic and environmental, collectively influence phenotype. 3. Pleiotropy: when a gene controls multiple phenotypic effects 4. Epistasis: When a gene at one locus alters the phenotypic expression of a gene at a second locus 5. Carrier: a person who is heterozygous for a recessive disease and therefore does not display the phenotype (disease). They are called carriers because although they are phenotypically normal with regard to the disorder, they can transmit the recessive allele to their offspring. They are heterozygotes and normal (Rr) DISEASES a. Recessively Inherited Disorders Tay-Sachs disease * Inherited disorder in humans where the brain cells of a child with the disease cannot metabolize certain lipids because a crucial enzyme does not working properly. * As the lipids accumulate in the brain cell, the child beings to suffer seizures, blindness, and degeneration of motor mental performance and dies within a few years. * Only children who inherit two copies of Tay-Sachs allele (HOMOZYGOUS) have the disease. Therefore at the organismal level, the Tay Sachs allele qualifies as recessive * The intermediate phenotype observed at the biochemical level is characteristic of incomplete dominance of either allele * At the molecular level, the normal allele and the Tay-Sachs allele are codominant because a person heterozygous for Tay Sachs disease does not have the disease symptoms, but the individual still produces equal number of normal and dysfunctional enzyme molecules Cystic Fibrosis * Most common lethal genetic disease in the U.S, strikes one out of every 2,500 people of European descent. * The normal allele for this gene codes for a membrane protein that functions in the transport of chloride ions between certain cells and the extracellular fluids. * A person who has the disease has two recessive alleles. * Two recessive alleles result in defective chloride transport channels in their plasma membrane. * Therefore they have a high conc. Of extracellular chloride which makes mucus thicker and sticker and it builds up in the pancreas, lungs, digestive tract, etc. leading to multiple (pleiotropic) effects. This includes poor absorption of nutrients from intestines, chronic bronchitis, recurrent bacterial infections, and disablement of a natural antibiotic made by some body cells. Sickle-Cell Disease * Most common inherited disorder among people of African descent, affects 1/400 of A.A. * Caused by the substitution of a single amino acid in the hemoglobin protein of red blood cells. * A person with the disease has 2 recessive alleles. * When the O2 content of an affected person’s blood is low, the sickle cell hemoglobin molecules aggregate into long rods that dorm the normal circular red blood cells in a shriveled sickle shape. * Sickled cells can clump blood vessels which = physical weakness, pain, organ damage, and even paralysis. * The multiple effects of a two recessive sickle-cell allele are another example of pleiotropy. * At the organismal level, the normal allele is incompletely dominant to the sickle-cell allele. * Heterozygotes of the Sick Cell disease have one sickle-cell allele and another normal allele. They are said to have the sickle-cell trait * Heterozygotes of the disease have a single copy of the sickle cell allele, and it reduces the frequency and severity of malaria attacks, especially among young children. * Therefore, about 1/10 A.A have the sickle cell trait because in tropical Africa, where infection with malaria parasite is common, the sickle-cell allele is more common as well because A.A’s with the sickle cell trait have a higher survival rate. * The presence of heterozygous amounts of sickle-cell hemoglobin results in lower parasite densities in the body! b. Dominant Inherited Disorders Achondroplasia * A form of dwarfism that occurs in one of every 250,000 people. Heterozygous individuals have the dwarf phenotype. * Everyone who is not an achondroplastic dwarf (99.99%) is homozygous for the RECESSIVE allele. * Dominant alleles that cause a lethal disease are much less common than recessive alleles that cause diseases. * If a lethal dominant allele causes the death of an offspring before they reproduce, the allele will not be passed on to future generations. A lethal recessive allele can be preserved from generation to generation by heterozygous carriers who have normal phenotypes). Huntington’s disease * A lethal dominant allele can escape elimination if it causes death only after an individual who carries the allele has reaches an advanced age. The individual w/ the disease could have already had children and given it to them, like the Huntington’s disease. * A degenerative disease of the nervous system that is caused by a lethal dominant allele that has no obvious phenotypic effect until the person is about 35-40 years old. * Deterioration of the nervous system is irreversible and inevitably fatal. * Affects 1/10,000 in the US * In modern tech, we can analyze DNA samples with a background of the disorder and track the Huntington’s allele to a locus near the tip of chromosome 4. YAY CHAPTER 15 Fruit Fly Lab * Thomas Hunt Morgan picked a species of fruit fly, Drosophila melanogaster for his work. * Fruit flies only have 4 fairs of chromosomes that are easily distinguishable w/ a light microscope. * They can breed really fast. * He found a mutation after a long time; a male fruit fly with MUTANT TYPE eyes: White eyes * Regular fruit flies have red eyes, called the WILD TYP * Wild Type: Trait that is common and is dominant * Mutant Type: Trait that is less common and recessive * Notation for the first mutant (non-wild type) had the subscript w. A superscript + identifies the wild type trait: w+. So all wild type traits (normal have a plus symbol and all mutant’s had no plus signs. * Only males had white eyes in the F2 generation so he concluded that a fly’s eye color was linked to its sex. * Concluded that the gene for white eye mutation was located only on the X chromosome and not on the Y chromosome because males only need one X to have the mutation. A female in the F2 generationw would need two X chromosomes with the recessive mutant allele (w) which was impossible because the F1 father had red eyes. SEX-LINKED GENES AND DISEASES a. Sex linked Gene: * A sex-linked gene is a gene that is located on either sex chromosome X or Y. The term has historically referred specifically to a gene on the X chromosomes. * Fathers can pass sex-linked alleles to all their daughters but to none of their sons (since the father HAD TO HAVE contributed a Y chromosome to make the child a son, then the X must come from the mother and therefore if the disease was on his X chromosome, it wouldn’t have passed on to his son). * Mothers can pass sex-linked alleles to both sons and daughters. * IF a sex-linked trait is due to a RECCESSIVE allele, a girl will only express the phenotype if and only if she is a homozygote. * For males, the term hemizygous is used since they only have ONE x and ONE y. Any male receiving the recessive allele from his mother will ALWAYS express the trait. Therefore more men than females have sex-linked recessive. b. Sex-Linked Diseases 1. Colorblindness Usually rare 2. Duchenne Muscular Dystrophy Affects about 1/3500 males born in the U.S. Characterized by a progressive weakening of the muscles and loss of coordination. Affected individuals rarely live past their early 20’s. The disorder is caused by the absence of a key muscle protein called dystrophin. Scientists have mapped the gene for this protein to a specific locus on the X chromosome. 3. Hemophilia Sex-linked recessive disorder defined by the absence of one or more of the proteins required for blood clotting. When a person w/ hemophilia is injured, bleeding is prolonged because a firm clot is slow to form. People with the disease are treated with injections of the missing protein. LINKED GENES * Linked genes are genes located on the same chromosome that tend to be inherited together in genetic crosses. * An example of a two linked genes on fruit flies is the gene for body type and wings. * In the fruit fly, the WILD (Normal) type for body color is GRAY and for wings are NORMAL wings. * In the fruit fly, the MUTANT type for body color is BLACK and for wings are VESTIGIAL wings. * In his experiment, if genes are located on different chromosomes, then the numbers for Gray-normal, Black-vestigial, Gray-Vestigial, and Black-Normal would be the same, but the #’s of the offspring are different because the genes are located on the same chromosome and the parent alleles are always inherited together. MAPS A genetic map is an order list of the genetic loci along a particular chromosome. * The father apart two genes are, the higher the probability that a crossover will occur between them and therefore the higher the recombination frequency. * So the greater the distance between two genes, the more points there are between them where crossing over can occur. A linkage map is a genetic map based on the recombination frequencies. Map Units are equivalent to a 1% recombination frequency. * So if the recombinant frequency is 17%, then the map unit would be 17. DISEASES DUE TO CHROMOSOMAL ALTERATIONS * NONDISJUNCTIO is when members of a pair of homologous chromosomes do not move apart properly during meiosis I or meiosis II. * ANEUPLIDY is when a zygote has an abnormal number of a chromosome. The zygote can be monosomic (missing one chromosome so it only has 1 chromosome) or trisomic (has an extra chromosome, so 3 chromosomes) * POLYPLOIDY is when organisms have more than two complete chromosome sets in all somatic cells. Down Syndrome (Trisomy 21) * An aneuploidy condition that affects around 1/700 children born in the U.S. * Usually the result of an extra chromosome 21, therefore each body cell has a total of 47 chromosomes * Includes characteristic facial features, short stature, heart defects, respiratory infection, and mental retardation. * Individuals w/ the disease are prone to developing leukemia and Alzheimer’s disease. * On average, people/ D.S have a life span shorter than normal and are sexually underdeveloped and sterile. * Frequency of Down syndrome increases w/ the age of the mother. * The extra chromosome can result from nondisjunction during meiosis I, and some research points to an age-dependent abnormality in a meiosis checkpoint that normally delays anaphase until all the kinetochores are attached to the spindle fiber (Like the M phase in the mitotic cell cycle). Klinefelter Syndrome * When an extra X chromosome is in a male, producing XXY. * Occurs about 1/2000 births. * People w/ the syndrome have male sex organs, but the testes are abnormally small and the man is sterile. * Even though the extra X is inactivated as Barr bodies in somatic cells, they can have some breast enlargement and other female body characteristics. They can also have subnormal intelligence. * Men with the disease tend to be taller than average Trisomy X * When a female has three X’s (XXX). * Occurs about 1/1000 live births * The females are healthy and cannot be distinguished from normal XX females except by karyotype. Turner Syndrome * Monosomy X, only one X in females * Occurs about 1/5000 births * Is the only known viable monosomy in humans * Although these X0 individuals are phenotypically female, they are sterile because their sex organs do not mature. * Most w/ the syndrome have normal intelligence. * When females that have Turner Syndrome are provided w/estrogen replacement therapy, they can develop secondary sex characteristics. Cri Du Chat (â€Å"cry of the cat†) * A disorder caused by a specific deletion in chromosome 5. * A child born w/ this syndrome is mentally retarded, has a small head w/ unusual facial features, and has a cry that sounds like the mewing of a distressed cat. * People w/ the disease usually die in infancy or early childhood. Chronic Myelogenous Leukemia (CML) * A disorder that occurs when a reciprocal translocation happens during mitosis of cells that will become white blood cells. * The exchange of a large portion of chromosome 22 w/ a small fragment from a tip of chromosome 9 produces a much shortened, easily recognized chromosome 22, called the Philadelphia chromosome. MITOCHONDRIAL DISEASES * They reduce the amount of ATP the cell can make. * RARE human disorders. * Mitochondrial mutations inherited from a person’s mother can contribute to some cases of diabetes, heart disease, and Alzheimer’s disease. Mitochondrial Myopathy * Causes weakness, intolerance of exercise, and muscle deterioration Leber’s Hereditary Optic Neuropathy * Can produce sudden blindness in people as young as in their 20s or 30s * 4 mutations found so far to cause this disorder affect oxidative phosphorylation during cellular respiration ANOTHER DISORDER Phenylketonuria (PKU) * Recessively inherited disorder that occurs about 1/10,000-15,000 births in the U.S. * Children w/ disease can’t properly metabolize the amino acid phenylalanine. * The compound and its by-product, phenylpyruvate, can accumulate to toxic levels in the blood, causing mental retardation.